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KMID : 0624620080410030217
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BMB Reports
2008 Volume.41 No. 3 p.217 ~ p.222
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2-D graphical representation of protein sequences and its application to coronavirus phylogeny
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Li Chun
Xing Lili
Wang Xin
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Abstract
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Based on a five-letter model of the 20 amino acids, we propose a new 2-D graphical representation of protein sequence. Then we transform the 2-D graphical representation into a numerical characterization that will facilitate quantitative comparisons of protein sequences. As an application, we construct the phylogenetic tree of 56 coronavirus spike proteins. The resulting tree agrees well with the established taxonomic groups. [BMB reports 2008; 41(3): 217-222]
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KEYWORD
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ALE-index, Coronavirus, Graphical representation, Phylogeny, Protein
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